Drug trial targets early warning signs of blood cancer

NCT ID NCT05102370

Summary

This small, early-stage study tested whether a drug called enasidenib could safely improve low blood cell counts in people with a condition called CCUS. CCUS involves abnormal blood cells and low counts but is not yet cancer, though it can increase the risk of developing blood cancers. Researchers wanted to see if blocking a specific mutated protein with this drug could help patients' blood counts recover.

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Contacts and locations

Locations

  • Cleveland Clinic (Data Collection Only)

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic (Data Collection Only)

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Bergen (Limited protocol activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited protocol activities)

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk-Commack (Limited protocol activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    Harrison, New York, 10604, United States

  • Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Ohio State University (Data Collection Only)

    Columbus, Ohio, 43210, United States

  • Oregon Health & Science University (Data Collection Only)

    Portland, Oregon, 97239, United States

  • Washington University (Data Collection and Specimen Analysis)

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.