Can a diabetes drug protect kidneys in heart failure patients?

NCT ID NCT06030843

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether empagliflozin, a diabetes drug, can prevent death, new dialysis, or lasting kidney damage in people with cardiorenal syndrome type 1—a condition where heart failure suddenly worsens kidney function. About 200 hospitalized adults will receive either empagliflozin or a placebo for 30 days. The goal is to see if the drug helps preserve kidney function and improve survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Empagliflozin 10 mg

What this could lead to

If it works, this could point toward a treatment that protects kidneys and reduces the need for dialysis in patients with heart and kidney failure.

What could go wrong

This is a mid-stage trial with 200 participants, so results may not apply to everyone. The drug may not improve outcomes and could cause side effects like dehydration or low blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardio-renal syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Medicine, Chulalongkorn University

    RECRUITING

    Bangkok, Pathumwan, 10330, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••