Can a diabetes drug protect kidneys in heart failure patients?

NCT ID NCT06030843

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether empagliflozin, a diabetes drug, can prevent death, new dialysis, or lasting kidney damage in people with cardiorenal syndrome type 1—a condition where heart failure suddenly worsens kidney function. About 200 hospitalized adults will receive either empagliflozin or a placebo for 30 days. The goal is to see if the drug helps preserve kidney function and improve survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Empagliflozin 10 mg
What this could lead to
If it works, this could point toward a treatment that protects kidneys and reduces the need for dialysis in patients with heart and kidney failure.
What could go wrong
This is a mid-stage trial with 200 participants, so results may not apply to everyone. The drug may not improve outcomes and could cause side effects like dehydration or low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Chulalongkorn University

    RECRUITING

    Bangkok, Pathumwan, 10330, Thailand