New drug tested to stop dangerous bleeding in rare blood disorder
NCT ID NCT05345197
Summary
This study is testing whether a medication called emicizumab can safely prevent bleeding episodes in adults with acquired hemophilia A, a rare but serious condition where the immune system attacks blood clotting factors. About 51 participants will receive weekly injections of the drug for at least 12 weeks while also receiving standard immune-suppressing treatments. Researchers will measure how many bleeding episodes occur and monitor for side effects to see if this approach offers better protection.
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Contacts and locations
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Locations
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Bleeding and Clotting Disorders Institute
Peoria, Illinois, 61614, United States
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Emory University
Atlanta, Georgia, 30308, United States
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Georgetown University
Washington D.C., District of Columbia, 20007, United States
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Hemophilia Center of Western Pennsylvania
Pittsburgh, Pennsylvania, 15213, United States
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Indiana Hemophilia and Thrombosis Center, Inc.
Indianapolis, Indiana, 46260, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Penn Blood Disorders Program, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Tulane University
New Orleans, Louisiana, 70112-2632, United States
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UCSD Hemophilia and Thrombosis Treatment Center
San Diego, California, 92121, United States
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UVA Comprehensive Cancer Center
Charlottesville, Virginia, 22908, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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University of Vermont Medical Center
Burlington, Vermont, 05401, United States
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Versiti Inc.
Milwaukee, Wisconsin, 53226, United States
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Washington Center for Bleeding Disorders
Seattle, Washington, 98101, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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