New preventive treatment shows promise for reducing bleeds in hemophilia a

NCT ID NCT04158648

Summary

This study tested a preventive treatment called emicizumab in people with mild or moderate hemophilia A who do not have inhibitors. The goal was to see if regular injections could safely reduce the number of bleeding episodes. Researchers measured how often participants bled and how the treatment affected their daily activities and quality of life.

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Contacts and locations

Locations

  • Amsterdam UMC Location AMC

    Amsterdam, 1105 AZ, Netherlands

  • CH de Bicetre

    Le Kremlin-Bicêtre, 94275, France

  • Cardiff and Vale NHS Trust

    Cardiff, CF14 4XW, United Kingdom

  • Charlotte Maxeke Johannesburg Hospital

    Johannesburg, 2193, South Africa

  • Childrens Hospital LA

    Los Angeles, California, 90027, United States

  • Cliniques Universitaires St-Luc

    Brussels, 1200, Belgium

  • Eastern Health - General Hospital

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • Great Ormond street Hospital for Children NHS Foundation Trust

    London, WC1N 3HR, United Kingdom

  • Groupe Hospitalier Necker Enfants Malades

    Paris, 75015, France

  • Hemophilia of Georgia Center for Bleeding & Clotting Disorders

    Atlanta, Georgia, 30308, United States

  • Hopital Cardio-vasculaire Louis Pradel

    Bron, 69677, France

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hospital Universitario la Paz

    Madrid, 28046, Spain

  • Indiana Hemophilia & Thrombosis center

    Indianapolis, Indiana, 46260, United States

  • Instytut Hematologii i Transfuzjologii

    Warsaw, 02-776, Poland

  • Kaye Edmonton Clinic

    Edmonton, Alberta, T6G 1Z1, Canada

  • Klinikum der Universität München, Campus Innenstadt

    München, 80336, Germany

  • Royal Free Hospital

    London, NW3 2QG, United Kingdom

  • UZ Leuven Gasthuisberg

    Leuven, 3000, Belgium

  • University of Michigan, C.S. Mott Children's Hospital

    Ann Arbor, Michigan, 48109, United States

  • Universitätsklinikum Bonn

    Bonn, 53127, Germany

  • Washington Institute for Coagulation

    Seattle, Washington, 98101, United States

Conditions

Explore the condition pages connected to this study.