New combo aims to keep cancer in check with fewer side effects

NCT ID NCT03264547

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 24 times

Summary

This study tested whether a combination of eribulin, pertuzumab, and trastuzumab works as well as the standard taxane-based combo for advanced HER2-positive breast cancer, but with better quality of life. 446 women who had not received chemotherapy for advanced disease took part. The goal was to see if the new combo could control the cancer for a similar amount of time while reducing side effects like numbness and tingling.

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Contacts and locations

Locations

  • Kanagawa Cancer Center

    Yokohama, Kanagawa, 241-8515, Japan

  • National Hospital Organization Osaka National Hospital

    Osaka, Osaka, 540-0006, Japan

Conditions

Explore the condition pages connected to this study.