New sepsis treatment trial targets deadly immune response
NCT ID NCT06694701
Summary
This study is testing whether a drug called emapalumab can help patients with severe sepsis who have a specific overactive immune response. It involves 75 adults in Greece with sepsis from infections like pneumonia, comparing two doses of the drug against a placebo. The main goal is to see if the treatment reduces organ failure scores and improves survival over 28 days.
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Contacts and locations
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Locations
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1st Department of Internal Medicine, Thriasio Elefsis General Hospital
Elefsina, Attica, Greece
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1st Intensive Care Unit, G. Papanikolaou Thessaloniki General Hospital
Thessaloniki, Greece
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3rd University Department of Internal Medicine, Sotiria Chest Diseases Athens General Hospital
Athens, Greece
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4th Department of Internal Medicine, ATTIKON University General Hospital
Athens, Greece
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Clinic of Intensive Care and Pulmonary Diseases, Aghioi Anargyroi Kifissia General Oncologic Hospital
Kifissia, Attica, Greece
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Department of Anesthesiology and Intensive Care, AHEPA Thessaloniki University General Hospital
Thessaloniki, Greece
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Intensive Care Unit I, KAT Attica General Hospital
Athens, Greece
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Intensive Care Unit of 1st University Department Respiratory Medicine, Sotiria Chest Diseases Athens General Hospital
Athens, Greece
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Intensive Care Unit of Center for Respiratory Failure, Sotiria Chest Diseases Athens General Hospital
Athens, Greece
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Intensive Care Unit, 424 General Military Training Hospital
Thessaloniki, Greece
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Intensive Care Unit, Aghios Dimitrios Thessaloniki General Hospital
Thessaloniki, Greece
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Intensive Care Unit, Alexandroupolis University General Hospital
Alexandroupoli, Greece
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Intensive Care Unit, Asklipieio Voulas General Hospital
Athens, Greece
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Intensive Care Unit, G. Gennimatas Thessaloniki General Hospital
Thessaloniki, Greece
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Intensive Care Unit, Ippokrateio Athens General Hospital
Athens, Greece
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Intensive Care Unit, Ippokrateio Thessaloniki General Hospital
Thessaloniki, Greece
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Intensive Care Unit, Korgialeneio-Benakeio HRC Athens General Hospital
Athens, Greece
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Intensive Care Unit, Laiko Athens General Hospital
Athens, Greece
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Intensive Care Unit, Papageorgiou Thessaloniki General Hospital
Thessaloniki, Greece
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Intensive Care Unit, Patras University General Hospital
Pátrai, Greece
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Intensive Care Unit, Theageneio Thessaloniki Cancer Hospital
Thessaloniki, Greece
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Intensive Care Unit, University General Hospital of Heraklion
Heraklion, Crete, Greece
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New Multivalent Intensive Care Unit, Sotiria Chest Diseases Athens General Hospital
Athens, Greece
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Ηigh Dependency Unit of Department of Clinical Therapeutics, Alexandra Athens General Hospital
Athens, Greece
Conditions
Explore the condition pages connected to this study.