New hope for advanced HER2 cancers? early trial combines novel drug with standard therapy
NCT ID NCT06328738
First seen Nov 19, 2025 · Last updated May 13, 2026 · Updated 22 times
Summary
This early-stage study is testing a new drug called ELVN-002 combined with trastuzumab (and sometimes chemotherapy) in adults with advanced HER2-positive solid tumors, including breast, colorectal, and gastric cancers. The main goals are to find the safest dose and understand side effects. About 275 participants will take part to see if this combination can help control the disease.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Asan Medical Center
Seoul, 05505, South Korea
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Azienda Ospedaliero Universitaria Pisana
Pisa, Italy
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Azienda Ospedaliero-Universitaria Renato Dulbecco
Catanzaro, Italy
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Azienda USL IRCCS di Reggio Emilia
Reggio Emilia, Italy
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BRCR Medical Center Inc.
Plantation, Florida, 33322, United States
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CHA Bundang Medical Center
Seongnam-si, 13496, South Korea
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CHU de Liège
Liège, Belgium
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CHU de Poitiers
Poitiers, 8600, France
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Clinica univeritaria Navarra - Pamplonas
Pamplona, Spain
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Clinica universitaria Navarra - Madrid
Madrid, 28027, Spain
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Cliniques Universitaires Saint-Luc
Brussels, Belgium
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Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy
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Fondazione Policlinico A. Gemelli IRCCS
Rome, 00168, Italy
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Fundacion Instituto Valenciano de Oncologia
Valencia, Spain
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GZA Ziekenhuizen - Campus Sint-Augustinus
Wilrijk, Belgium
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Hospital Beata Maria Ana
Madrid, 28007, Spain
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Hospital Universitari Dexeus - Grupo Quironsalud
Barcelona, Spain
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Institut de Cancérologie Strasbourg Europe
Strasbourg, 67033, France
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Institut de Cancérologie de l'Ouest
Saint-Herblain, France
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Institut du Cancer de Montpellier - Val D'Aurelle
Montpellier, 34090, France
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Instituto de Investigacion Oncologica Vall d'Hebron (VHIO) - EPON
Barcelona, Spain
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Istituto Europeo di Oncologia
Milan, Italy
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NEXT Oncology-Hospital Quironsalud Barcelona
Barcelona, 08023, Spain
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NEXT Virginia
Fairfax, Virginia, 22031, United States
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Radboud UMC
Nijmegen, Netherlands
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START Barcelona_HM Nou Delfos
Barcelona, 08023, Spain
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START Madrid - Hospital Universitario Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Seoul National University Hospital
Soeul, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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The Catholic University of Korea, St. Vincent's Hospital
Suwon, 16247, South Korea
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Washington University
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.