New drug combo shows promise for rare bone marrow failure
NCT ID NCT02099747
First seen Apr 30, 2026 · Last updated Apr 30, 2026
Summary
This study tested whether adding eltrombopag to standard immunosuppressive therapy improves early recovery in patients with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. 202 participants received either standard treatment (horse antithymocyte globulin plus cyclosporine) or the same plus eltrombopag. The main goal was to see if more patients achieved complete blood count recovery at 3 months with the added drug.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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'Federico II' Medical School
Naples, Italy
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AMC
Amsterdam, Netherlands
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AOU Città della Salute e della Scienza di Torino
Turin, Italy
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Azienda Ospedaliera Papa Giovanni XXIII
Bergamo, Italy
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Centre Hospitalier Lyon-Sud
Lyon, France
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City Hospital
Nottingham, United Kingdom
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Donostia Hospital
Donostia / San Sebastian, Spain
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Fondazione IRCCS ca Granda Ospedale
Milan, Italy
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Hopital Jean Minjoz
Besançon, France
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Hospital La Fe
Valencia, Spain
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Hospital Universitari Germans Trias I Pujol
Badalona, Spain
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Hôpital Haut-Lévèque
Bordeaux, France
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Hôpital Huriez
Lille, France
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Hôpital Purpan
Toulouse, France
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Institut Català d'Oncologia - Hospital Duran i Reynals
Barcelona, Spain
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Istituto G. Gaslini children's Hospital
Genova, Italy
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King's College Hospital
London, United Kingdom
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La Sapienza University Hospital
Rome, Italy
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Leiden University Medical Center
Leiden, Netherlands
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Pontchaillou Hospital
Rennes, France
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San Martino Hospital
Genova, Italy
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St. Bartholomew's Hospital
London, United Kingdom
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St. James Hospital
Leeds, United Kingdom
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St. Louis Hospital
Paris, France
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UMCG
Groningen, Netherlands
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UMCU
Utrecht, Netherlands
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University Hospital Basel
Basel, Switzerland
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University Hospital Bern
Bern, Switzerland
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University Hospital Zürich
Zurich, Switzerland
Conditions
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