New dosing strategy tested for advanced blood cancer treatment

NCT ID NCT05014412

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This study tested a new way of giving the drug elranatamab to people with multiple myeloma that has come back or stopped responding to other treatments. The goal was to see if starting with lower 'step-up' doses and then giving the drug less often could make it safer and more effective. Researchers enrolled 86 participants to receive the drug as an injection and monitored them for at least two years.

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Contacts and locations

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Locations

Blood Cancer and Stem Cell Transplant Clinic

San Antonio, Texas, 78229, United States
Cancer Care & Hematology - Fort Collins

Fort Collins, Colorado, 80528, United States
China Medical University Hospital

Taichung, 40447, Taiwan
Cleveland Clinic Taussig Cancer Institute

Cleveland, Ohio, 44195, United States
East Jefferson General Hospital

Metairie, Louisiana, 70006, United States
East Jefferson General Hospital Bone Marrow Transplant Clinic

Metairie, Louisiana, 70006, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Guy's and St Thomas' NHS Foundation Trust

London, SE1 9RT, United Kingdom
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Huntsman Cancer Institute, University of Utah

Salt Lake City, Utah, 84112, United States
Japanese Red Cross Medical Center

Shibuya-ku, Tokyo, 150-8935, Japan
King's College Hospital NHS Foundation Trust

London, SE5 9RS, United Kingdom
Kobe City Medical Center General Hospital

Kobe, Hyōgo, 650-0047, Japan
MSK Basking Ridge

Basking Ridge, New Jersey, 07920, United States
MSK Bergen

Montvale, New Jersey, 07645, United States
MSK Commack

Commack, New York, 11725, United States
MSK Monmouth

Middletown, New Jersey, 07748, United States
MSK Nassau

Uniondale, New York, 11553, United States
MSK Westchester

Harrison, New York, 10604, United States
Mayo Clinic

Scottsdale, Arizona, 85259, United States
Mayo Clinic Hospital

Phoenix, Arizona, 85054, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street).

New York, New York, 10021, United States
Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy

Long Island City, New York, 11101, United States
Methodist Healthcare System of San Antonio dba Methodist Hospital

San Antonio, Texas, 78229, United States
Methodist Hospital Investigational Pharmacy

San Antonio, Texas, 78229, United States
Methodist Plaza Clinical Trials Office

San Antonio, Texas, 78229, United States
Nagoya City University Hospital

Nagoya, Aichi-ken, 467-8602, Japan
National Cancer Center Hospital

Chuo-ku, Tokyo, 104-0045, Japan
National Taiwan University Hospital

Taipei, 10002, Taiwan
Poudre Valley Health System (PVHS)

Fort Collins, Colorado, 80528, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
St. David's South Austin Medical Center

Austin, Texas, 78704, United States
Taipei Veterans General Hospital

Taipei, 11217, Taiwan
Texas Oncology-South Austin

Austin, Texas, 78745, United States
The Regents of the University of Michigan

Ann Arbor, Michigan, 48109, United States
The Royal Marsden NHS Foundation Trust

London, SW3 6JJ, United Kingdom
The Royal Marsden NHS Foundation Trust

Surrey, SM2 5PT, United Kingdom
Tulane University

New Orleans, Louisiana, 70112, United States
UCHealth Cancer Care & Hematology - Greeley

Greeley, Colorado, 80634, United States
UCHealth Cancer Care & Hematology - Loveland

Loveland, Colorado, 80538, United States
UF Health Shands Cancer Hospital

Gainesville, Florida, 32608, United States
UF Health Shands Hospital

Gainesville, Florida, 32610, United States
UF Health Shands Hospital Pharmacy Investigational Drug Service - Main

Gainesville, Florida, 32610, United States
University College London Hospitals NHS Foundation Trust

London, NW1 2PG, United Kingdom
University College London Hospitals NHS Foundation Trust NIHR

London, W1T 7HA, United Kingdom
University Hospital,Kyoto Prefectural University of Medicine

Kyoto, 602-8566, Japan
University Hospitals Birmingham NHS Foundation Trust

Birmingham, B15 2TH, United Kingdom
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Utah

Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.

MULTIPLE MYELOMA