New cancer vaccine targets 'Undruggable' KRAS mutations in early trial

NCT ID NCT04853017

Summary

This early-stage trial tested a new immunotherapy called ELI-002 in 25 people with pancreatic, colorectal, lung, and other cancers that have specific KRAS mutations. The treatment was given after standard therapy to target any remaining cancer cells and prevent recurrence. Researchers primarily wanted to see if the treatment was safe and if it could reduce cancer markers in the blood.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Northwell Health

    Lake Success, New York, 11042, United States

  • Tennessee Oncology - Centennial Clinic

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.