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Is chronic elbow pain really a Whole-Body nerve problem?

NCT ID NCT07827898

Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Lateral epicondylitis, often called tennis elbow, causes pain and tenderness on the outside of the elbow and can linger despite treatment. Researchers are comparing 128 people with chronic lateral epicondylitis to healthy controls to see whether those with elbow pain have lower pain thresholds in distant, unaffected areas like the shin, which would suggest the nervous system is more sensitive overall. The study also measures tendon changes on ultrasound, grip function, fear of movement, and psychosocial factors to understand what drives ongoing disability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study links chronic elbow pain to widespread nerve sensitization, it could point toward treatments that target the nervous system rather than only the tendon.
What could go wrong
This is a small observational study that measures people at a single point in time, so it can show associations but cannot prove what causes chronic elbow pain or whether treating central sensitization would help.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients applying to the Physical Medicine and Rehabilitation outpatient clinic of Derince Training and Research Hospital and the Physical Medicine and Rehabilitation outpatient clinic of Sultan Abdulhamid Han Training and Research Hospital will be evaluated. Those who volunteer to participate in the study and meet the inclusion criteria will have their measurements and surveys completed at Sultan Abdulhamid Han Training and Research Hospital.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1. CASE GROUP Inclusion Criteria: Have unilateral lateral elbow pain persisting for at least 3 months Have a visual analog scale score of 4/10 or higher Have tenderness upon palpation of the common extensor tendon and/or lateral epicondyle region Experience elbow pain that occurs or worsens with hand grip or lateral elbow pain that occurs with resistant static contraction or stretching of the wrist extensors Have read and signed the volunteer consent form (VCF) Exclusion Criteria: * Having undergone surgery on the upper extremity or cervical region before * Presence of cervical or shoulder pathology * Mechanical symptoms in the elbow (locking, limited range of motion) and other elbow pathologies * History of trauma to the elbow * Presence of upper extremity neurological deficit * History of fibromyalgia, central nervous system disease, or rheumatic disease * Last 1 month history of physical therapy or injection for lateral epicondylitis * Pregnancy 2. HEALTHY GROUP Inclusion Criteria: * Not having experienced elbow pain before * Having read and signed the volunteer agreement form (BGOF) 2.Exclusion criteria * Presence of upper extremity, shoulder, or neck pain within the last year * History of upper extremity fractures * Presence of neurological deficits

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Conditions

The condition(s) this trial relates to.

epicondylitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central sensitization Lateral epicondylitis

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sultan Abdülhamid Han Eğitim ve Araştırma Hastanesi

    RECRUITING

    Istanbul, Turkey (Türkiye)

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