New study tracks Elacestrant's Real-World impact on advanced breast cancer

NCT ID NCT07563595

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 500 postmenopausal women with advanced ER+ HER2- breast cancer that has an ESR1 mutation. Participants receive elacestrant as part of their normal care. Researchers will track quality of life, side effects, and how the cancer responds over time. The goal is to understand how well this drug works outside of clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elacestrant (Orserdu®)

What this could lead to

If successful, this study could provide real-world evidence on how well elacestrant controls advanced breast cancer and improves quality of life for patients with ESR1 mutations.

What could go wrong

This is an observational study, not a controlled trial, so results may be influenced by other factors. It does not test a new treatment but gathers data on existing use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm estrogen-receptor positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gemeinschaftspraxis für Hämatologie und Onkologie

    RECRUITING

    Ravensburg, 88212, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Praxis für interdisziplinäre Onkologie & Hämatologie

    RECRUITING

    Freiburg im Breisgau, 79110, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Louise Frauen- und Kinderklinik

    RECRUITING

    Paderborn, 33098, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••