Head-to-Head trial tests new shot for rare, debilitating blood vessel disease

NCT ID NCT04157348

Summary

This study compares two injectable medications, benralizumab and mepolizumab, for treating a rare autoimmune disease called EGPA. It involves 140 adults whose EGPA keeps coming back or hasn't responded well to standard steroid treatments. The main goal is to see which drug is better at helping patients achieve and maintain remission while reducing their need for steroids.

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Contacts and locations

Locations

  • Research Site

    Denver, Colorado, 80206, United States

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    Ann Arbor, Michigan, 48109, United States

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    Rochester, Minnesota, 55905-0001, United States

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    Albuquerque, New Mexico, 87106, United States

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    Great Neck, New York, 11021, United States

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    New York, New York, 10021, United States

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    Philadelphia, Pennsylvania, 19104, United States

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    Denison, Texas, 75020, United States

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    Seattle, Washington, 98115, United States

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    Brussels, 1070, Belgium

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    Brussels, 1090, Belgium

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    Calgary, Alberta, T2N 4Z6, Canada

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    Hamilton, Ontario, L8N 4A6, Canada

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    Toronto, Ontario, M5G 1E2, Canada

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    Toronto, Ontario, M5T 3A9, Canada

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    Dijon, 21079, France

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    Marseille, 13915, France

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    Montpellier, 34090, France

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    Nantes, 44093, France

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    Paris, 75014, France

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    Paris, 75877, France

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    Suresnes, 92151, France

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    Toulouse, 31059, France

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    Bamberg, 96049, Germany

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    Freiburg im Breisgau, 79106, Germany

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    Hamburg, 20251, Germany

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    Kirchheim, 73230, Germany

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    Lübeck, 23538, Germany

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    Ashkelon, 7830604, Israel

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    Beersheba, 84101, Israel

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    Jerusalem, 91120, Israel

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    Ramat Gan, 52621, Israel

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    Rehovot, 7661041, Israel

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    Tel Aviv, 6423906, Israel

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    Cuneo, 12100, Italy

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    Florence, 50141, Italy

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    Milan, 20132, Italy

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    Milan, 20162, Italy

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    Naples, 80131, Italy

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    Roma, 00168, Italy

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    Torino, 10128, Italy

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    Chiba, 260-0877, Japan

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    Kita-gun, 761-0793, Japan

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    Sagamihara-shi, 228-0815, Japan

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    Sendai, 980-8574, Japan

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    Shinjuku-ku, 162-8666, Japan

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    Cambridge, CB2 0QQ, United Kingdom

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    Leicester, LE3 9QP, United Kingdom

  • Research Site

    London, SE19RT, United Kingdom

  • Research Site

    Portsmouth, PO6 3LY, United Kingdom

Conditions

Explore the condition pages connected to this study.