Eggshells for youthful skin? new study tests supplement against wrinkles
NCT ID NCT07493850
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether a daily eggshell membrane supplement called EMC-CAP-2025A can improve age-related skin issues like wrinkles, dryness, and loss of elasticity. Sixty healthy adults aged 30 to 55 will take either the supplement or a placebo for 60 days. Researchers will measure changes in wrinkles, skin hydration, and firmness using 3D imaging and other tools.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- EMC-CAP-2025A (eggshell membrane-based dietary supplement)
- What this could lead to
- If it works, this could offer a natural supplement option for reducing facial wrinkles and improving skin hydration and elasticity.
- What could go wrong
- This is a small Phase 2 trial with only 60 participants, so results may not apply to everyone. As a dietary supplement, any effects are likely modest and not comparable to medical treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Feb 2026
- Expected to finish
-
May 2026
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
30 to 55 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Individuals who are willing to understand and sign a written informed consent form prior to the study. 2. Healthy male and female individuals aged between 30 to 55 years (both values included). 3. Individuals showing symptoms of aging, with mild to moderate wrinkles in crow's feet area based on PI discretion. 4. Individuals with any one of the following skin conditions along with mild to moderate wrinkles: 1. Under-eye dark circles 2. Hyperpigmentation spots (blemish) (post-inflammatory hyperpigmentation, acne marks, age spots, sunspots) 3. Dry dull skin 5. Individuals willing to maintain stable dietary patterns and maintain adequate hydration every day throughout the study 6. Individuals who are willing to attend all scheduled study visits at the test center and agree to refrain from applying any topical products (e.g.,moisturizers, creams, or similar treatments) 24 hours prior to each visit. 7. Willingness to participate in the study and comply with the study procedures and required visits. Exclusion Criteria: 1. Individuals having an allergy to any of the components of the IP. 2. Use of another investigational product within 90 days prior to the screening visit. 3. Individuals with any dermatologic disorders or skin conditions that could interfere with the evaluation of proprietary supplement's effects. 4. Individuals having an underlying disease or surgical or medical condition that could put them at risk in the opinion of Principal Investigator, including anyuncontrolled chronic or serious disease that would prevent participation in the study, such as cancer, AIDS, diabetes, obesity, renal impairment, psychiatricdisorder, compromised immunity, etc. 5. Individuals having a history of self-reported allergies to cosmetic and/or sunscreen products. 6. Individuals who have used or are unwilling to abstain from using any topical or systemic skin-treatment products or dietary supplements with claims toimprove skin hydration, firmness, anti-aging, anti-wrinkle, skin lightening, or dyschromia correction - including those containing alpha/beta/poly-hydroxyacids, salicylic acid, vitamin C, collagen, hyaluronic acid, soy, CoQ-10, chondroitin sulfate, hydroquinone, corticosteroids, tretinoin, retinoids, or anycombination thereof - within 1 month prior to screening or during the study period. 7. Individuals currently using oral or topical health foods, supplements, pharmaceuticals, or cosmetics that claim whitening or skin-texture improvementeffects such as but not limited to glutathione, cysteine, placenta-based extracts, Vitamins C/E/A (retinol), astaxanthin, lycopene, etc., and who cannotrefrain from using them during the study period. 8. Individuals who have undergone any facial cosmetic or aesthetic procedures, including beauty injections, deep or superficial-to-mid chemical peels,dermabrasion, laser resurfacing, Thermage, tanning, cosmetic surgery, or any equivalent high-energy or anti-aging facial treatments, within 3 months priorto the screening visit. 9. Individuals who had hormone replacement therapy within 3 months preceding the screening visit. 10. Individuals who have used oral contraceptives or had changed contraceptive method within 3 months prior to the screening visit, or plan to modifycontraception treatment within the duration of study. 11. Employees of the clinical labs or other testing firms or laboratories, as well as those of cosmetic or raw-material manufacturers of topical products ortheir suppliers. 12. Individuals who are undergoing medical treatment or have a medical history of lupus, scleroderma, atopic dermatitis, acne, facial scarring, psoriasis,eczema, and other autoimmune/inflammatory scaly skin disorders. 13. History of uncontrolled hypertension with systolic blood pressure more than or equal to 140 mmHg and/or diastolic blood pressure more than or equalto 90 mmHg. 14. Females who are pregnant/planning to be pregnant/lactating or taking any oral contraceptives. 15. History of smoking or currently smoking and also using any form of smokeless tobacco. 16. Individuals having a history of or ongoing drug or alcohol abuse.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
C.L.A.I.M.S. Private Limited
Mumbai, India
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