Biosimilar breast cancer drug trial pulled before it began

NCT ID NCT06884254

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

This study aimed to compare a biosimilar version of pertuzumab (EG1206A) to the original drug (Perjeta) in people with HER2-positive, hormone receptor-negative early breast cancer. Participants would have received either drug alongside trastuzumab and chemotherapy before surgery, then continued treatment after surgery. However, the trial was withdrawn before enrolling any patients, so no data were collected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Methodist Health System Clinical Research Institute

    Dallas, Texas, 75023, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pertuzumab (biosimilar EG1206A)

What this could lead to

If successful, this could provide a more affordable biosimilar option for treating HER2-positive breast cancer.

What could go wrong

The study was withdrawn before any participants enrolled, so no results are available. Biosimilars may differ slightly in effectiveness or safety from the original drug.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.