Can a new injection calm Sjogren's nerve damage?

NCT ID NCT07760818

Not yet recruiting Disease control Sponsor: argenx Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether an experimental drug called efgartigimod can reduce nerve damage and pain in adults with Sjogren's disease. Participants will receive either the drug or a placebo as a subcutaneous injection. The study measures changes in neuropathy symptoms and quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
efgartigimod PH20 given as a subcutaneous injection
What this could lead to
If successful, this could offer a new treatment to reduce nerve pain and damage in people with Sjogren's disease, improving their quality of life.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not be conclusive. The drug may not work for everyone and could have side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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