Antibody therapy aims to keep colon cancer from returning
NCT ID NCT00002968
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase III trial tested whether adding a monoclonal antibody called edrecolomab to surgery helps people with stage II colon cancer live longer or stay cancer-free longer. About 2,100 participants were randomly assigned to receive either the antibody or no additional treatment after surgery. The study tracked survival and how long it took for the cancer to come back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
edrecolomab (monoclonal antibody 17-1A)
What this could lead to
If successful, this could provide an additional treatment option to reduce the risk of cancer returning after surgery for stage II colon cancer.
What could go wrong
This trial is completed but results may not show a clear benefit over surgery alone. Monoclonal antibodies can cause infusion reactions or allergic responses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cancer and Leukemia Group B
Chicago, Illinois, 60606, United States