New drug EDI048 takes on stomach bug in human trial
NCT ID NCT07249463
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study tests an experimental drug called EDI048 for cryptosporidiosis, a diarrheal disease caused by a parasite. Healthy adults will be deliberately infected with the parasite and then given either EDI048 or a placebo to see if the drug reduces diarrhea severity. The goal is to gather evidence that could lead to a treatment for children, who are most affected by this infection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- EDI048 (an experimental oral drug)
- What this could lead to
- If successful, this could point toward a new treatment for cryptosporidiosis, especially for children who currently lack effective options.
- What could go wrong
- This is an early Phase 2 trial in only 96 healthy adults, not patients. The drug may not work as well in real-world settings or in children, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cinn Children Hosp Medical Center
RECRUITINGCincinnati, Ohio, 45229-3039, United States
-
Pharmaron Inc
RECRUITINGBaltimore, Maryland, 21201, United States
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