New drug EDI048 takes on stomach bug in human trial

NCT ID NCT07249463

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called EDI048 for cryptosporidiosis, a diarrheal disease caused by a parasite. Healthy adults will be deliberately infected with the parasite and then given either EDI048 or a placebo to see if the drug reduces diarrhea severity. The goal is to gather evidence that could lead to a treatment for children, who are most affected by this infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EDI048 (an experimental oral drug)

What this could lead to

If successful, this could point toward a new treatment for cryptosporidiosis, especially for children who currently lack effective options.

What could go wrong

This is an early Phase 2 trial in only 96 healthy adults, not patients. The drug may not work as well in real-world settings or in children, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cryptosporidiosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Pharmaron Inc

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact