Brain scans reveal how shock therapies affect depression

NCT ID NCT07533773

Recruiting now Knowledge-focused Sponsor: The Second Hospital of Anhui Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study will use a brain imaging technique called fNIRS to see how electroconvulsive therapy (ECT) and magnetic seizure therapy (MST) change brain activity in people with major depression. Researchers will compare the two treatments in 60 adults to understand their effects on mood and thinking. The goal is to learn which therapy works better for different patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Electroconvulsive therapy or magnetic seizure therapy
What this could lead to: If successful, this study could help doctors choose between ECT and MST based on how each affects brain function and cognition in depression.
What could go wrong: This is an early-stage observational study with only 60 participants, so results may not apply to everyone. It measures brain activity, not long-term outcomes.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER (MDD)

Contacts and locations

Locations

The Second Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, Anhui, 230601, China

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