New device may simplify ECMO removal, reduce bleeding risks

NCT ID NCT07019662

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special suture device (Perclose ProStyle) can close the artery as safely as standard methods (manual pressure or surgery) after removing ECMO tubes in patients with severe heart and lung failure. About 102 adults on VA-ECMO will be randomly assigned to the device or standard care. The goal is to see if the device reduces complications like bleeding, blood clots, or vessel injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Abbott Perclose™ ProStyle™ Suture-Mediated Closure System
What this could lead to
If successful, this could provide a less invasive, safer way to close arteries after ECMO removal, reducing bleeding and recovery time.
What could go wrong
This is a relatively small, early-stage trial (102 participants) comparing a device to varied standard practices, so results may not apply broadly. Device failure could cause bleeding or vessel injury.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Universitäres Herz- und Gefäßzentrum Frankfurt ZIM - Med. Clinic 3 - Cardiology and Angiology

    RECRUITING

    Frankfurt, Germany

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz - Zentrum für Kardiologie

    RECRUITING

    Mainz, Germany

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