New eye drops could help kids with lazy eye that Won't go away
NCT ID NCT07554131
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding echothiophate iodide eye drops to standard atropine therapy can improve vision in children aged 3 to 18 with refractory amblyopia (lazy eye that hasn't improved with standard treatment). Twenty participants will use atropine nightly for 12 weeks, and if no improvement after 4 weeks, they'll also use echothiophate drops in the weaker eye for 8 weeks. The goal is to see if this combination can boost visual acuity and depth perception.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Echothiophate iodide eye drops
- What this could lead to
- If it works, this could offer a new treatment option for children with lazy eye that hasn't improved with standard therapy, potentially improving vision and depth perception.
- What could go wrong
- This is a small early-phase trial with only 20 participants, so results may not apply to all children. The drug may cause side effects like eye irritation or blurred vision, and it's unclear if benefits will last after stopping treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dean McGee Eye Institute
Oklahoma City, Oklahoma, 73104, United States