New eye drops could help kids with lazy eye that Won't go away

NCT ID NCT07554131

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding echothiophate iodide eye drops to standard atropine therapy can improve vision in children aged 3 to 18 with refractory amblyopia (lazy eye that hasn't improved with standard treatment). Twenty participants will use atropine nightly for 12 weeks, and if no improvement after 4 weeks, they'll also use echothiophate drops in the weaker eye for 8 weeks. The goal is to see if this combination can boost visual acuity and depth perception.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Echothiophate iodide eye drops

What this could lead to

If it works, this could offer a new treatment option for children with lazy eye that hasn't improved with standard therapy, potentially improving vision and depth perception.

What could go wrong

This is a small early-phase trial with only 20 participants, so results may not apply to all children. The drug may cause side effects like eye irritation or blurred vision, and it's unclear if benefits will last after stopping treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amblyopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dean McGee Eye Institute

    Oklahoma City, Oklahoma, 73104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact