Scientists investigate blood vessel cells to unlock secrets of bleeding disorder
NCT ID NCT07358013
First seen Jan 30, 2026 · Last updated Jun 23, 2026 · Updated 23 times
Summary
This observational study aims to understand how endothelial colony-forming cells (ECFCs) behave in people with von Willebrand disease (VWD) and acquired von Willebrand syndrome (AVWS) compared to healthy individuals. Researchers will collect blood samples from 48 participants to isolate ECFCs and measure how they produce and release von Willebrand factor. The goal is to learn more about the underlying biology of these bleeding disorders.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, A.B.Bonomi Hemophilia and Thrombosis Center
RECRUITINGMilan, 20122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could improve understanding of how blood vessel cells contribute to von Willebrand disease, potentially pointing toward new ways to diagnose or manage the condition.
What could go wrong
This is a small, early-stage observational study with only 48 participants. It is not testing a treatment, so it will not directly lead to a cure or therapy.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.