Scientists investigate blood vessel cells to unlock secrets of bleeding disorder

NCT ID NCT07358013

Recruiting now Knowledge-focused Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study aims to understand how endothelial colony-forming cells (ECFCs) behave in people with von Willebrand disease (VWD) and acquired von Willebrand syndrome (AVWS) compared to healthy individuals. Researchers will collect blood samples from 48 participants to isolate ECFCs and measure how they produce and release von Willebrand factor. The goal is to learn more about the underlying biology of these bleeding disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could improve understanding of how blood vessel cells contribute to von Willebrand disease, potentially pointing toward new ways to diagnose or manage the condition.
What could go wrong: This is a small, early-stage observational study with only 48 participants. It is not testing a treatment, so it will not directly lead to a cure or therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired von willebrand syndrome von Willebrand disease (hereditary or acquired)

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACQUIRED VON WILLEBRAND DISEASE VON WILLEBRAND DISEASE (VWD)

Contacts and locations

Locations

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, A.B.Bonomi Hemophilia and Thrombosis Center
RECRUITING

Milan, 20122, Italy

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