One Patient's lifeline: donor t cells take on EBV lymphoma

NCT ID NCT06391814

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a personalized treatment for a young adult with a severe EBV-related lymphoma that occurred after a stem cell transplant. The patient received up to four infusions of specially grown immune cells from their original stem cell donor. The goal was to see if these cells could safely control the lymphoma and improve the body's ability to fight the virus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EBV-specific T cells (donor-derived immune cells)

What this could lead to

If successful, this approach could offer a way to control EBV-related lymphoma after a stem cell transplant without causing severe graft-versus-host disease.

What could go wrong

This was a single-patient study, so results may not apply to others. The treatment carries risks like graft-versus-host disease or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

EBV-positive T-cell lymphoproliferative disorder of childhood Epstein-Barr virus-associated lymphoproliferative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ciusss-Emtl

    Montreal, Quebec, H1T 2M4, Canada