Ebola vaccine immunity under the microscope: how long does protection last?

NCT ID NCT05313139

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how long the Ebola vaccine (rVSV-ZEBOV) protects health workers in the Democratic Republic of the Congo. Researchers measured immune cells and antibodies in 133 vaccinated health workers to see if protection lasts beyond 1-2 years. The goal is to understand if booster shots are needed, especially after recent Ebola cases in previously vaccinated people.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rVSV-ZEBOV vaccine

What this could lead to

If successful, this could show how long the Ebola vaccine protects health workers and whether booster doses are needed.

What could go wrong

This is an observational study, not a treatment trial. It only measures immune responses and cannot prove the vaccine prevents future infections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut National de Recherche Biomédicale (INRB)

    Goma, Democratic Republic of the Congo

  • Institut National de Recherche Biomédicale (INRB)

    Kinshasa, Democratic Republic of the Congo