Can switching ventilator mode early save lives? new trial aims to find out
NCT ID NCT07519512
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether changing the ventilator settings early—from full control to a mode where the patient does some of the work—helps critically ill adults get off the machine faster. About 1,600 patients across 10 ICUs will be randomly assigned to either early switching or usual care. The main goal is to see if more patients are successfully breathing without a ventilator by day 28.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- early transition to assisted ventilation (behavioral intervention)
- What this could lead to
- If it works, this could lead to shorter time on ventilators and better outcomes for critically ill patients.
- What could go wrong
- This is an early-stage trial with no phase, so results are uncertain. The open-label design may introduce bias, and findings may not apply to all ICU patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MECHANICAL VENTILATOR CARE are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zhongda Hospital, School of Medicine, Southeast University
RECRUITINGNanjing, Jiangsu, 210009, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.