Simple ventilator switch could get ICU patients off breathing machines faster
NCT ID NCT07519512
First seen Apr 14, 2026
Summary
This study looks at whether switching critically ill patients from a fully controlled ventilator to a mode that lets them do some of the breathing work (assisted ventilation) within 6 hours helps them get off the machine successfully within 28 days. About 1,600 adults in ICUs who need a breathing tube for at least 48 hours will take part. Hospitals will alternate between the early-switch strategy and usual care to see which works better.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Zhongda Hospital, School of Medicine, Southeast University
RECRUITINGNanjing, Jiangsu, 210009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
early transition to assisted ventilation (Pressure Support Ventilation)
What this could lead to
If successful, this could show that a simple change in ventilator settings helps critically ill patients breathe on their own sooner, reducing time on machines.
What could go wrong
This is a behavioral strategy, not a drug, so benefits may be modest. Results depend on how each ICU implements the change, and the open-label design could introduce bias.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.