Battle of the scalpels: which surgery is best for early rectal cancer?

NCT ID NCT02885142

Terminated Disease control Sponsor: Assistance Publique Hopitaux De Marseille Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two procedures for removing early-stage rectal cancer or precancerous growths: endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM). Both are less invasive than traditional surgery. The goal was to see which one removes the tumor more completely and safely. The trial was terminated early, so the results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: procedure
What this could lead to: If this trial succeeds, it could show which procedure is better for removing early rectal cancer with fewer complications.
What could go wrong: The trial was terminated early, so results may be incomplete. Both procedures are already used, so the benefit may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anal carcinoma anus neoplasm rectal cancer rectal carcinoma rectum adenoma rectum carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAL CANCER

Contacts and locations

Locations

Assistance Publique Hôpitaux de Marseille

Marseille, 13354, France

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