Could early ibrutinib stop CLL before it starts?

NCT ID NCT03207555

First seen Sep 30, 2025 · Last updated Apr 30, 2026 · Updated 18 times

Summary

This study tested whether giving the drug ibrutinib early to people with chronic lymphocytic leukemia (CLL) who have high-risk features but no symptoms yet is better than waiting until symptoms appear. Twenty-three participants took ibrutinib for up to 24 months. The goal was to see if early treatment could lead to complete or partial remission and delay disease progression.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.