Targeted drug shows promise for rare bile duct cancer

NCT ID NCT04238715

Completed Disease control Sponsor: Eisai Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called E7090 in 63 people with advanced bile duct cancer that has a specific genetic change (FGFR2 fusion). Participants had already tried chemotherapy without success. The goal was to see if the drug could shrink tumors. Results help determine if this targeted therapy offers a new treatment option for this hard-to-treat cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Apert syndrome cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLANGIOCARCINOMA

Contacts and locations

Locations

Affiliated Hospital of Hebei University

Baoding, Hebei, China
Affilicataed Cancer Hospital of Harbin Medical University

Harbin, Heilongjiang, China
Anhui Provincial Hospital

Hefei, Anhui, China
Beijing Tsinghua Chang Gung Memorial Hospital

Beijing, Beijing Municipality, China
Beijing Youan Hospital Affiliated to Capital Medical University

Beijing, Beijing Municipality, China
Beijng Cancer Hospital

Beijing, Beijing Municipality, China
Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China
Eisai Trial Site 1

Ube-Shi, Yamaguchi, Japan
Eisai Trial Site 10

Nagoya, Aichi-ken, Japan
Eisai Trial Site 11

Matsuyama, Ehime, Japan
Eisai Trial Site 12

Kyoto, Japan
Eisai Trial Site 13

Hirakata, Osaka, Japan
Eisai Trial Site 14

Matsuyama, Ehime, Japan
Eisai Trial Site 15

Fukuoka, Japan
Eisai Trial Site 16

Kashiwa, Chiba, Japan
Eisai Trial Site 17

Suita, Osaka, Japan
Eisai Trial Site 18

Chiba, Japan
Eisai Trial Site 19

Kochi, Japan
Eisai Trial Site 2

Sapporo, Hokkaido, Japan
Eisai Trial Site 20

Kagoshima, Japan
Eisai Trial Site 21

Niigata, Japan
Eisai Trial Site 22

Sendai, Miyagi, Japan
Eisai Trial Site 23

Tsu, Mie-ken, Japan
Eisai Trial Site 24

Wakayama, Japan
Eisai Trial Site 3

Mitaka, Tokyo, Japan
Eisai Trial Site 4

Chuo-ku, Tokyo, Japan
Eisai Trial Site 5

Bunkyo-ku, Tokyo, Japan
Eisai Trial Site 6

Koto-ku, Tokyo, Japan
Eisai Trial Site 7

Yokohama, Kanagawa, Japan
Eisai Trial Site 8

Kanazawa, Ishikawa-ken, Japan
Eisai Trial Site 9

Sunto-gun, Shizuoka, Japan
Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China
Fujian Provincial Hospital

Fuzhou, Fujian, China
Guangdong Province Traditional Chinese Medical Hospital

Guangzhou, Guangdong, China
Henan Cancer Hospital

Zhengzhou, Henan, China
Hunan provincial people's hospital

Changsha, Hunan, China
Jiangsu Province Hospital

Nanjing, Jiangsu, China
Jilin Cancer Hospital

Changchun, Jilin, China
Nantong Tumor Hospital

Nantong, Jiangsu, China
Ningbo First Hospital

Ningbo, Zhejiang, China
Peking Union Medical University Hospital

Beijing, Beijing Municipality, China
Peking University Shenzhen Hospital

Shenzhen, Guangdong, China
Shandong Cancer Hospital

Jinan, Shandong, China
The First Affiliated Hospital of Bengbu Medical College

Bengbu, Anhui, China
The First Affiliated Hospital of Soochow

Suzhou, Jiangsu, China
The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China
The First Affiliated Hospital, College of Medicine, Zhejiang University

Hangzhou, Zhejiang, China
The First Affiliated Hospital, Sun Yat-sen Univeristy

Guangzhou, Guangdong, China
The Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China
The Third Xiangya Hospital of Central South University

Changsha, Hunan, China
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China
Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China
West China Hospital of Sichuan University

Chengdu, Sichuan, China
Xiangya Hospital of Central South University

Changsha, Hunan, China
Zhongshan Hospital Fudan University

Shanghai, Shanghai Municipality, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.