New hope for Tough-to-Treat lymphoma: experimental drug DZD8586 under study

NCT ID NCT06539195

First seen Jan 07, 2026 · Last updated May 05, 2026 · Updated 19 times

Summary

This study tests an experimental drug called DZD8586 in 59 adults with diffuse large B-cell lymphoma that has returned or stopped responding to prior treatments. The goal is to see if the drug can shrink tumors and to understand its side effects and how the body processes it. Participants take the drug alone, without other cancer treatments, and are monitored closely.

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Contacts and locations

Locations

  • National Clinical Research Center for Blood Diseases, Blood Disease Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College

    Tianjin, Tianjin Municipality, 300020, China

  • Research Site

    Hefei, Anhui, 230031, China

  • Research Site

    Beijing, Beijing Municipality, 100083, China

  • Research Site

    Guangzhou, Guangdong, 510060, China

  • Research Site

    Nanning, Guangxi, 530016, China

  • Research Site

    Zhengzhou, Henan, 450003, China

  • Research Site

    Wuhan, Hubei, 430023, China

  • Research Site

    Changsha, Hunan, 410031, China

  • Research Site

    Jinan, Shandong, 250117, China

  • Research Site

    Linyi, Shandong, 276002, China

  • Research Site

    Xi’an, Shanxi, 710061, China

  • Research Site

    Chengdu, Sichuan, 610041, China

  • Research Site

    Tianjin, Tianjin Municipality, 300181, China

  • Research Site

    Hangzhou, Zhejiang, 310009, China

Conditions

Explore the condition pages connected to this study.