New combo therapy targets hard-to-treat lymphoma
NCT ID NCT07059650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called DZD8586 combined with standard treatments for diffuse large B-cell lymphoma (DLBCL), a fast-growing blood cancer. It involves 150 adults whose cancer is either newly diagnosed or has returned after initial therapy. The goal is to see if the combination shrinks tumors and to check for side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anhui Provincial Cancer Hospital
RECRUITINGHefei, China
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Guangdong Provincial People's Hospital
RECRUITINGGuangzhou, China
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Henan Cancer Hospital
RECRUITINGZhengzhou, China
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Hunan Cancer Hospital
NOT_YET_RECRUITINGChangsha, China
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Linyi Cancer Hospital
RECRUITINGLinyi, China
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Peking University Third Hospital
RECRUITINGBeijing, China
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Shanxi Cancer Hospital
RECRUITINGTaiyuan, China
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, China
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The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITINGXi'an, China
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The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITINGHangzhou, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, China
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West China Hospital of Sichuan University
RECRUITINGChengdu, China
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Zhujiang Hospital of Southern Medical University
RECRUITINGGuangzhou, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A shot at safer CAR t: early brain protection for lymphoma patients?
- Can donor immune cells be engineered to fight blood cancer?
- Can a simple blood test spot lymphoma earlier?
- Can a Light-Based device spot dangerous infection risk without a blood draw?