Smart blood tests guide lung cancer treatment in new trial

NCT ID NCT04841811

First seen May 13, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This phase 3 study tests a two-step approach for people with a specific type of advanced lung cancer (EGFR-mutant, stage III). First, patients take a targeted pill called almonertinib. Then, based on a sensitive blood test (MRD) and team evaluation, they may get surgery or radiation, followed by more almonertinib. The goal is to see if this personalized plan helps control the cancer longer. About 192 adults aged 18-70 with good performance status are eligible.

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Contacts and locations

Locations

  • Guangdong Lung cancer institute

    Guangzhou, Guangdong, 510080, China

Conditions

Explore the condition pages connected to this study.