New drug cocktail shows promise against tough cancers
NCT ID NCT02499328
First seen Nov 12, 2025 · Last updated May 14, 2026 · Updated 27 times
Summary
This study tested combinations of the immunotherapy durvalumab with two other experimental drugs (danvatirsen or AZD5069) in 340 adults with advanced solid tumors or head & neck cancer that had spread or come back. The goal was to find safe doses and see if the combinations could shrink tumors. While not a cure, the approach aims to control the disease by boosting the immune system's attack on cancer cells.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
Birmingham, Alabama, 35294, United States
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Duarte, California, 91010, United States
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La Jolla, California, 92093, United States
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Los Angeles, California, 90024, United States
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Los Angeles, California, 90089, United States
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Orange, California, 92868-3298, United States
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San Francisco, California, 94158, United States
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Denver, Colorado, 80218, United States
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Plantation, Florida, 33324, United States
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Sarasota, Florida, 34232, United States
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Lafayette, Indiana, 47905, United States
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Boston, Massachusetts, 02111, United States
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Detroit, Michigan, 48201, United States
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Billings, Montana, 59101, United States
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Morristown, New Jersey, 07960, United States
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Cincinnati, Ohio, 45267-2827, United States
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Houston, Texas, 77030, United States
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Fairfax, Virginia, 22031, United States
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Seattle, Washington, 98109, United States
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Antwerp, 2020, Belgium
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Brussels, 1000, Belgium
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Brussels, 1200, Belgium
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Edegem, 2650, Belgium
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Namur, 5000, Belgium
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Berlin, 12200, Germany
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Cologne, 50670, Germany
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Dresden, 1307, Germany
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Frankfurt, 60488, Germany
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Hamburg, 20246, Germany
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Hanover, 30625, Germany
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Jena, 07743, Germany
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München, 81675, Germany
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Milan, 20133, Italy
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Barcelona, 08035, Spain
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Hospitalet deLlobregat, 08907, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Toledo, 45004, Spain
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Birmingham, B15 2TH, United Kingdom
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London, SE1 9RT, United Kingdom
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London, SW3 6JB, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Surrey, SM2 5PT, United Kingdom
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Taunton, TA1 5DA, United Kingdom
Conditions
Explore the condition pages connected to this study.