New hope for endometrial cancer: drug combo shows promise

NCT ID NCT06746116

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests a combination of drugs (durvalumab, chemotherapy, and olaparib) as a first treatment for people with advanced or recurrent endometrial cancer that has a specific genetic marker (pMMR). The goal is to see how safe and tolerable the treatment is. About 85 people in Spain will take part, and they will be followed for up to 3 years.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    A Coruña, 15006, Spain

  • Research Site

    Alicante, 03010, Spain

  • Research Site

    Barakaldo, 48903, Spain

  • Research Site

    Barcelona, 08035, Spain

  • Research Site

    Córdoba, 14004, Spain

  • Research Site

    El Palmar, 30120, Spain

  • Research Site

    Girona, 17007, Spain

  • Research Site

    L'Hospitalet de Llobregat, 08908, Spain

  • Research Site

    Las Palmas de Gran Canaria, 35016, Spain

  • Research Site

    Madrid, 28034, Spain

  • Research Site

    Madrid, 28041, Spain

  • Research Site

    Madrid, 28046, Spain

  • Research Site

    Madrid, 28807, Spain

  • Research Site

    Málaga, 29010, Spain

  • Research Site

    Pamplona, 31008, Spain

  • Research Site

    Salamanca, 37007, Spain

  • Research Site

    San Sebastián, 20014, Spain

  • Research Site

    Santander, 39008, Spain

  • Research Site

    Seville, 41013, Spain

  • Research Site

    Valencia, 46009, Spain

  • Research Site

    Valencia, 46010, Spain

  • Research Site

    Valencia, 46026, Spain

  • Research Site

    Vigo, 36312, Spain

  • Research Site

    Zaragoza, 50009, Spain