Radiation may stop Dupuytren's hand disease in its tracks
NCT ID NCT07661342
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether radiation therapy can prevent Dupuytren's contracture—a condition where fingers bend toward the palm—from progressing or coming back after treatment. About 158 adults will receive radiation to the hand, and researchers will measure changes in finger straightness over time. The goal is to find a non-surgical way to control the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy
- What this could lead to
- If it works, this could offer a way to slow or stop Dupuytren's contracture from getting worse, reducing the need for surgery.
- What could go wrong
- This is an early-stage trial with only 158 participants, and radiation therapy carries risks like skin irritation or long-term side effects. It may not prevent progression for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Greenwich Hospital
Greenwich, Connecticut, 06830, United States