New hope for kids with painful swallowing disorder

NCT ID NCT04394351

Summary

This study tested whether the drug dupilumab could safely reduce inflammation and improve symptoms in children with eosinophilic esophagitis (EoE), a chronic condition that makes swallowing difficult. Over 100 children participated, receiving either the drug or a placebo for 16 weeks, with some continuing treatment for up to three years. The main goal was to see if dupilumab could significantly lower the number of inflammatory cells in the esophagus.

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Contacts and locations

Locations

  • Regeneron Study Site

    Phoenix, Arizona, 85016, United States

  • Regeneron Study Site

    Little Rock, Arkansas, 72202, United States

  • Regeneron Study Site

    Los Angeles, California, 90027, United States

  • Regeneron Study Site

    San Francisco, California, 94143, United States

  • Regeneron Study Site

    Aurora, Colorado, 80045, United States

  • Regeneron Study Site

    St. Petersburg, Florida, 33701, United States

  • Regeneron Study Site

    Atlanta, Georgia, 30322, United States

  • Regeneron Study Site

    Atlanta, Georgia, 30342, United States

  • Regeneron Study Site

    Chicago, Illinois, 60611, United States

  • Regeneron Study Site

    Indianapolis, Indiana, 46202, United States

  • Regeneron Study Site

    Iowa City, Iowa, 52242, United States

  • Regeneron Study Site

    Boston, Massachusetts, 02111, United States

  • Regeneron Study Site

    Boston, Massachusetts, 02114, United States

  • Regeneron Study Site

    Boston, Massachusetts, 02115, United States

  • Regeneron Study Site

    Lincoln, Nebraska, 68510, United States

  • Regeneron Study Site

    New York, New York, 10029, United States

  • Regeneron Study Site

    New York, New York, 10032, United States

  • Regeneron Study Site

    New York, New York, 10065, United States

  • Regeneron Study Site

    Chapel Hill, North Carolina, 27599, United States

  • Regeneron Study Site

    Cincinnati, Ohio, 45229, United States

  • Regeneron Study Site

    Cleveland, Ohio, 44106, United States

  • Regeneron Study Site

    Philadelphia, Pennsylvania, 19104, United States

  • Regeneron Study Site

    Dallas, Texas, 75207, United States

  • Regeneron Study Site

    Fort Worth, Texas, 76104, United States

  • Regeneron Study Site

    Houston, Texas, 77030, United States

  • Regeneron Study Site

    Milwaukee, Wisconsin, 53226, United States

  • Regeneron Study Site

    London, Ontario, N6A 5W9, Canada

Conditions

Explore the condition pages connected to this study.