New hope for kids with food allergy esophagitis: drug may allow safe food reintroduction

NCT ID NCT05247866

First seen Nov 10, 2025 · Last updated Apr 26, 2026 · Updated 22 times

Summary

This study tested whether dupilumab, a drug that blocks type 2 inflammation, can help children and young adults (ages 6-25) with eosinophilic esophagitis safely add back foods like milk, egg, soy, or wheat into their diet. The 21 participants were monitored for changes in esophageal inflammation and symptoms. The goal was to see if the drug could reduce the need for strict food avoidance and improve quality of life.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.