New hope for kids with swallowing trouble: drug targets esophagus inflammation
NCT ID NCT04394351
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 22 times
Summary
This study tested a drug called dupilumab in 102 children with active eosinophilic esophagitis (EoE), a condition where the esophagus becomes inflamed, making swallowing painful. The goal was to see if dupilumab could reduce inflammation better than a placebo after 16 weeks. Researchers also checked for long-term safety and symptom improvement over up to 160 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Regeneron Study Site
Phoenix, Arizona, 85016, United States
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Regeneron Study Site
Little Rock, Arkansas, 72202, United States
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Regeneron Study Site
Los Angeles, California, 90027, United States
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Regeneron Study Site
San Francisco, California, 94143, United States
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Regeneron Study Site
Aurora, Colorado, 80045, United States
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Regeneron Study Site
St. Petersburg, Florida, 33701, United States
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Regeneron Study Site
Atlanta, Georgia, 30322, United States
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Regeneron Study Site
Atlanta, Georgia, 30342, United States
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Regeneron Study Site
Chicago, Illinois, 60611, United States
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Regeneron Study Site
Indianapolis, Indiana, 46202, United States
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Regeneron Study Site
Iowa City, Iowa, 52242, United States
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Regeneron Study Site
Boston, Massachusetts, 02111, United States
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Regeneron Study Site
Boston, Massachusetts, 02114, United States
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Regeneron Study Site
Boston, Massachusetts, 02115, United States
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Regeneron Study Site
Lincoln, Nebraska, 68510, United States
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Regeneron Study Site
New York, New York, 10029, United States
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Regeneron Study Site
New York, New York, 10032, United States
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Regeneron Study Site
New York, New York, 10065, United States
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Regeneron Study Site
Chapel Hill, North Carolina, 27599, United States
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Regeneron Study Site
Cincinnati, Ohio, 45229, United States
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Regeneron Study Site
Cleveland, Ohio, 44106, United States
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Regeneron Study Site
Philadelphia, Pennsylvania, 19104, United States
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Regeneron Study Site
Dallas, Texas, 75207, United States
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Regeneron Study Site
Fort Worth, Texas, 76104, United States
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Regeneron Study Site
Houston, Texas, 77030, United States
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Regeneron Study Site
Milwaukee, Wisconsin, 53226, United States
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Regeneron Study Site
London, Ontario, N6A 5W9, Canada
Conditions
Explore the condition pages connected to this study.