Promising AKN treatment trial halted early

NCT ID NCT05608499

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 39 times

Summary

This study tested Duobrii, a steroid-retinoid cream, for early-stage acne keloidalis nuchae (AKN) — a chronic scarring condition on the back of the scalp that mainly affects Black men. The trial aimed to see if the cream could reduce lesion counts and improve pain and itching over 12 weeks. Only 15 people were enrolled before the study was terminated, so results are limited.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

Conditions

Explore the condition pages connected to this study.