Common antidepressant could curb opioid use after knee surgery

NCT ID NCT06423716

Summary

This study is testing whether a medication called duloxetine, taken before and after knee replacement surgery, can help patients use fewer opioid painkillers during recovery. Researchers will compare 150 patients with knee osteoarthritis who receive either duloxetine or a placebo pill for 8 weeks total. The main goal is to see if the duloxetine group consumes significantly less opioid medication in the first week after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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