Can a single pill cut opioid use after hip surgery?
NCT ID NCT06807866
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single 60 mg dose of duloxetine, given before total hip replacement surgery, can reduce the amount of narcotic painkillers patients need afterward. Researchers will compare duloxetine to a placebo in 64 adults. The goal is to see if this approach leads to better pain control and less reliance on opioids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
duloxetine
What this could lead to
If it works, this could offer a simple way to reduce opioid use and improve pain control after hip replacement surgery.
What could go wrong
This is a small, early-phase trial with only 64 participants. Duloxetine may not reduce pain or opioid use better than placebo, and it can cause side effects like nausea or dizziness.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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