Study sheds light on mysterious low white blood cell condition in kids
NCT ID NCT06547931
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looked back at medical records of 150 children who have a genetic trait called Duffy-null, which is linked to naturally low levels of a type of white blood cell (neutrophils). The goal was to find out how many of these children also have an immune system that attacks their own neutrophils, and whether the severity of the low counts is tied to infections. The research helps doctors better understand this common but poorly studied condition in children.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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150 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Pediatric patients sent to our laboratory for the search for anti-neutrophil antibodies in the suspicion of immune neutropenia
- Ages
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Up to 16 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * presence of Duffy-null phenotype Exclusion Criteria: * absence of Duffy-null phenotype
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Ca' Granda Ospedale Maggioe Policlinico
Milan, 20122, Italy