Double-Team attack: new CAR-T therapy targets two cancer markers to outsmart relapse
NCT ID NCT07523555
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new type of CAR-T cell therapy that targets two different markers on cancer cells at once, aiming to prevent the cancer from escaping treatment. It is for adults with several types of blood cancers that have come back or not responded to standard treatments. Participants receive an infusion of their own immune cells that have been engineered to attack their specific cancer based on biomarker testing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dual-target CAR-T cells (CD19/CD22, CD19/CD20, BCMA/CD19, BCMA/CD38, BCMA/GPRC5D, CD33/CD123, CD33/CLL1, or CD5/CD7)
What this could lead to
If successful, this could provide a more effective treatment option for people with hard-to-treat blood cancers by reducing the chance of cancer cells escaping the therapy.
What could go wrong
This is an early-phase trial (phase 1/2) with a small number of participants, so results may not apply to everyone. CAR-T therapy can cause serious side effects like cytokine release syndrome.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Peking University Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, 518036, China
Contact Phone: •••-•••-•••• Email: •••••@•••••