New whooping cough vaccine shows promise for toddlers
NCT ID NCT07213089
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new booster vaccine called DTaPgen in 290 healthy toddlers aged 15 to 36 months. The goal was to see if it works as well as a currently licensed vaccine to protect against whooping cough, diphtheria, and tetanus. Children received a single shot, and researchers measured their immune response and any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DTaPgen vaccine (recombinant acellular pertussis combined with diphtheria and tetanus)
What this could lead to
If successful, this could provide a new booster option to protect young children against whooping cough, potentially with fewer side effects than current vaccines.
What could go wrong
This is a mid-stage trial with only 290 toddlers, so results may not apply to all children. The vaccine may not prove as effective or safe as the licensed version in larger studies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kamphaengphet Hospital
Kamphaeng Phet, Changwat Kamphaeng Phet, 62000, Thailand
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Phaholpolpayuhasena Hospital
Kanchanaburi, Kanchanaburi, 71000, Thailand
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Vaccine Trial Centre (VTC), Faculty of Tropical Medicine, Mahidol University
Bangkok, Bangkok, 10400, Thailand