New whooping cough vaccine shows promise for toddlers
NCT ID NCT07213089
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new booster vaccine called DTaPgen in 290 healthy toddlers aged 15 to 36 months. The goal was to see if it works as well as a currently licensed vaccine to protect against whooping cough, diphtheria, and tetanus. Children received a single shot, and researchers measured their immune response and any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DTaPgen vaccine (recombinant acellular pertussis combined with diphtheria and tetanus)
- What this could lead to
- If successful, this could provide a new booster option to protect young children against whooping cough, potentially with fewer side effects than current vaccines.
- What could go wrong
- This is a mid-stage trial with only 290 toddlers, so results may not apply to all children. The vaccine may not prove as effective or safe as the licensed version in larger studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kamphaengphet Hospital
Kamphaeng Phet, Changwat Kamphaeng Phet, 62000, Thailand
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Phaholpolpayuhasena Hospital
Kanchanaburi, Kanchanaburi, 71000, Thailand
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Vaccine Trial Centre (VTC), Faculty of Tropical Medicine, Mahidol University
Bangkok, Bangkok, 10400, Thailand
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New vaccine trial aims to shield teens and adults from whooping cough
- Thousands monitored: is the whooping cough vaccine safe in real life?
- Whooping cough vaccine safety under the microscope in thailand
- Scientists deliberately infect volunteers with whooping cough to speed up vaccine research
- Massive U.S. study to see if whooping cough vaccine is safe for pregnant women and babies
- Whooping cough vaccine safety checked in 2,700 thai moms and babies