New pill takes on tough cancers in first human trial
NCT ID NCT07189403
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests an oral drug called DS9051b in 40 people with advanced adrenocortical carcinoma or metastatic castration-resistant prostate cancer. The main goal is to check safety and find the right dose, while also looking for any signs that the drug might shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DS9051b (oral drug)
What this could lead to
If it works, this could point toward a new treatment option for advanced adrenal or prostate cancers that have stopped responding to other therapies.
What could go wrong
This is a very early, small Phase 1 trial focused on safety, not proof of effectiveness. The drug may not shrink tumors or may cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brown University
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact
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Centre Oscar Lambret
NOT_YET_RECRUITINGVillejuif, 94800, France
Contact
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Columbia University
RECRUITINGNew York, New York, 10032, United States
Contact
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Florida Cancer Specialists
RECRUITINGSarasota, Florida, 34232, United States
Contact
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Oncopole Claudius Regaud
RECRUITINGToulouse, 31100, France
Contact
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Royal Marsden
NOT_YET_RECRUITINGLondon, SW3 6JJ, United Kingdom
Contact