New cancer drug DS5361b enters first human trials

NCT ID NCT07182591

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 28 times

Summary

This early-stage trial tests a new drug called DS5361b, alone or with another drug (pembrolizumab), in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug shrinks tumors. About 192 participants will take part across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Research Site

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • Research Site

    RECRUITING

    Irving, Texas, 75039, United States

  • Research Site

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Research Site

    NOT_YET_RECRUITING

    Fairfax, Virginia, 22031, United States

  • Research Site

    RECRUITING

    Chiba, 277-8577, Japan

  • Research Site

    RECRUITING

    Kōtoku, 135-8550, Japan

Conditions

Explore the condition pages connected to this study.