New hope for advanced tumors? first human trial of DS-3939a begins

NCT ID NCT05875168

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This early-phase study tests a new drug called DS-3939a in about 540 people with advanced solid tumors that have spread or cannot be removed. The main goals are to check safety and see if the drug shrinks tumors. Participants must have measurable disease and good organ function.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Asan Medical Center

    WITHDRAWN

    Seoul, 05505, South Korea

  • Assistance Publique- de Marseille

    RECRUITING

    Marseille, 13005, France

  • Beijing Cancer Hospital

    NOT_YET_RECRUITING

    Beijing, 100142, China

  • Cancer Institute Hospital of Jfcr

    RECRUITING

    Kōtoku, 135-8550, Japan

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69008, France

  • Chu Strasbourg

    RECRUITING

    Strasbourg, 67091, France

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Hospital Regional Universitario de Malaga

    RECRUITING

    Málaga, 29010, Spain

  • Hospital Universitari Vall D'Hebron

    RECRUITING

    Barcelona, 8035, Spain

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

  • Hospital Universitario Ramon Y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Virgen Macarena

    RECRUITING

    Seville, 41009, Spain

  • Huntsman Cancer Institute, University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Institut Claudius Regaud

    RECRUITING

    Toulouse, 31059, France

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Kansai Medical University Hospital

    RECRUITING

    Hirakata-shi, 573-1191, Japan

  • Kindai University Hospital

    RECRUITING

    Ōsaka-sayama, 589-8511, Japan

  • McGill University Health Center

    NOT_YET_RECRUITING

    Montreal, H4A 3J1, Canada

  • National Cancer Center Hospital

    RECRUITING

    Chūōku, 104-0045, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa, 277-8577, Japan

  • Next Madrid

    RECRUITING

    Pozuelo de Alarcón, 28223, Spain

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Osaka International Cancer Institute

    RECRUITING

    Osaka, 541-8567, Japan

  • Princess Margaret Cancer Center

    ACTIVE_NOT_RECRUITING

    Toronto, M5G2M9, Canada

  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Sendai Kousei Hospital

    RECRUITING

    Sendai, 981-0914, Japan

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Shandong Cancer Hospital

    RECRUITING

    Jinan, 250117, China

  • Shanghai East Hospital

    RECRUITING

    Shanghai, 200120, China

  • The Medical College of Wisconsin, INC

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • The Second Peoples Hospital of Neijiang

    RECRUITING

    Neijiang, 641000, China

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

  • University of Kansas Medical Center

    RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Texas M.D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

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