First human test of new brain cancer drug targets genetic flaw

NCT ID NCT03030066

Summary

This is an early-stage study to test the safety and initial effects of an experimental drug called DS-1001b in adults with recurrent glioma, a type of brain tumor. The drug specifically targets tumors that have a particular genetic change called an IDH1-R132 mutation. The main goals are to find a safe dose and see how the body processes the drug, while also checking for any early signs that it might help control the tumor.

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Contacts and locations

Locations

  • National Cancer Center Hospital

    Tokyo, Japan

Conditions

Explore the condition pages connected to this study.