New eye drop tested for severe dry eye relief

NCT ID NCT05136170

Summary

This study tested whether adding a new eye drop called cenegermin (Oxervate) to standard cyclosporine treatment could better help people with severe dry eye from Sjogren's syndrome. For 4 weeks, 85 participants used either the new drop or a placebo (vehicle) three times a day, while continuing their usual medication. Researchers measured if it improved tear production, reduced eye damage, and eased symptoms like dryness and discomfort.

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Contacts and locations

Locations

  • AOU Gaspare Rodolico - Ospedale San Marco

    Catania, 95123, Italy

  • AOU Policlinico Umberto I - Dipartimento Organi di Senso - Clinica Oculistica

    Roma, 00161, Italy

  • Houston Eye Associates HEA - Gramercy Location

    Houston, Tennessee, 77025, United States

  • Lugene Eye Institute - Glendale Office

    Glendale, California, 91204, United States

  • OCLI (Ophthalmic Consultants of Long Island)

    Garden City, New York, 11530, United States

  • Scheie Eye Institute

    Philadelphia, Pennsylvania, 19104, United States

  • The Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Toyos Clinic - Nashville

    Nashville, Tennessee, 37215, United States

  • Tufts University School of Medicine (TUSM) - New England Eye Center/Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • Università degli Studi di Milano - Ospedale San Giuseppe - UO Oculistica

    Milan, 20123, Italy

Conditions

Explore the condition pages connected to this study.