Eye drop study reveals hidden link between bacteria and dry eye relief
NCT ID NCT06936462
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This completed study looked at how two types of eye drops—cyclosporine A and hyaluronic acid—change the community of bacteria living on the eye's surface in people with dry eye syndrome. Fifty adults were randomly assigned to receive either cyclosporine plus hyaluronic acid or hyaluronic acid alone for 12 weeks. Researchers collected eye surface samples and measured symptoms using standard questionnaires. The goal was to see if changes in the eye's microbiome relate to symptom improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cyclosporine A and hyaluronic acid eye drops
- What this could lead to
- If successful, this could help explain how the eye's natural bacteria influence dry eye symptoms and point toward microbiome-based treatments.
- What could go wrong
- This is a small, early-stage study with only 50 participants and high dropout. Results may not apply to all dry eye patients, and the microbiome findings are exploratory.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hallym University, Kangnam Sacred Heart Hospital
Seoul, Seoul, 07441, South Korea
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Other studies related to the condition(s) this trial covers.
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