Eye drop study reveals hidden link between bacteria and dry eye relief
NCT ID NCT06936462
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This completed study looked at how two types of eye drops—cyclosporine A and hyaluronic acid—change the community of bacteria living on the eye's surface in people with dry eye syndrome. Fifty adults were randomly assigned to receive either cyclosporine plus hyaluronic acid or hyaluronic acid alone for 12 weeks. Researchers collected eye surface samples and measured symptoms using standard questionnaires. The goal was to see if changes in the eye's microbiome relate to symptom improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cyclosporine A and hyaluronic acid eye drops
What this could lead to
If successful, this could help explain how the eye's natural bacteria influence dry eye symptoms and point toward microbiome-based treatments.
What could go wrong
This is a small, early-stage study with only 50 participants and high dropout. Results may not apply to all dry eye patients, and the microbiome findings are exploratory.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hallym University, Kangnam Sacred Heart Hospital
Seoul, Seoul, 07441, South Korea