New drug combo aims to stop deadly inflammation after major heart surgery

NCT ID NCT06966687

Summary

This study is testing whether two drugs, Ulinastatin and Thymosin α1, given during emergency surgery for a torn aorta (aortic dissection), can reduce dangerous body-wide inflammation and prevent multiple organ failure. It will enroll 200 adult patients who need this urgent surgery. The goal is to see if this drug combination lowers the risk of severe complications that are a major cause of death after this type of operation.

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Contacts and locations

Locations

  • Beijing Anzhen Hospital

    Beijing, Beijing Municipality, China

  • Shanghai East Hospital Tongji University

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Guangzhou Medical University

    Guangzhou, Guangdong, China

  • West China Hospital

    Chengdu, Sichuan, China

Conditions

Explore the condition pages connected to this study.